Another gene associated with adipogenesis and possibly the low-grade inflammation of obesity is the ETS protooncogene 2 transcriptional factor gene (ETS2; OMIM * 164740), which encodes the ETS2 proto-oncogene and transcription factor, which specifically recognizes and binds to the core motif DNA sequence GGAA/T of target genes [133]. This evidence concerns the gene ETS2 and obesity due to melanocortin 4 receptor deficiency.