POMC and obesity due to melanocortin 4 receptor deficiency: Carbohydrate metabolism markers in individuals with FASDs were not correlated with ACTH and cortisol levels, but a positive association with fasting glucose (R = 0.193, p < 0.005) and triglycerides (R = 0.143, p < 0.05) were noticed in children and adolescents with overweight and obesity [66].