Besides, some recent studies focusing on early time-restricted eating patterns (eTRE) illustrated that consuming food at earlier times of the day (dinner was not eaten) and extending the length of the night fast could produce metabolic health improvements, including weight loss, improved insulin sensitivity, fasting insulin, and reduced serum glucose excursions after glucose loading in healthy individuals, as well as subjects with prediabetes [38,39]. Here, INS is linked to prediabetes syndrome.