in both wild-type and TGFβ-deficient mice after the induction of colorectal carcinogenesis by AOM + DSS [69], a finding that appears to differ from our observations for the Lachnospiraceae family, including Lachnoclostridium spp.; however, we do note that the abundance of this taxa is reduced at the study end point in mice fed the TWD, which have much more severe tumor outcomes. Here, TGFB1 is linked to infectious otitis media.