TGFB1 and neoplasm: in both wild-type and TGFβ-deficient mice after the induction of colorectal carcinogenesis by AOM + DSS [69], a finding that appears to differ from our observations for the Lachnospiraceae family, including Lachnoclostridium spp.; however, we do note that the abundance of this taxa is reduced at the study end point in mice fed the TWD, which have much more severe tumor outcomes.