Among the Cornus mas flavonoids identified in our study, naringenin was presented by Fallahi et al. in their experiment performed on diabetic rats as a factor that might improve the endothelial function of the aorta [43], kaempferol was described by Xiao et al. in their study realized in apolipoprotein E-deficient mice as an inhibitor of the aorta oxidative stress and atherosclerotic lesion [44] while Ren et al. in their review, exposed this flavonoid properties in DM alleviation [45]. This evidence concerns the gene APOE and diabetes mellitus.