IL10 and influenza: Among the top 15 most significant canonical pathways perturbed after exposure to NRCWE-051 (SWCNTs-pristine) at 6 μg/mouse were agranulocyte/granulocyte adhesion and diapedesis, communication between innate and adaptive immune cells, the role of hypercytokinemia/hyperchemokinemia in the pathogenesis of influenza, IL-10 signaling, and LXR/RXR activation (Figure 5A).