Researchers report that C21 steroidal glycosides can inhibit tumor cells by regulating the Wnt/β-catenin signaling pathway, TLR4/MyD88/NF-κB, AKT signaling pathway, PI3K/AKT/mTOR signaling pathway, and Hippo pathway [8,34,35]. The gene discussed is MTOR; the disease is neoplasm.