As shown in Figure 7A, B, the levels of IL-6 and TNF-α in the Bil group (23.09 ± 2.34 pg/mL, p < 0.01, 121.14 ± 5.08 ng/L, p < 0.05) were visibly higher than those in the control group (13.39 ± 4.17 pg/mL, 79.62 ± 18.61 ng/L), indicating that liver damage induced by hyperbilirubinemia may stimulate the production of inflammatory factors. Here, IL6 is linked to Hyperbilirubinemia.