For this reason, some of the molecular targets highly expressed in a variety of cancer cells and related to this process are those belonging to the Bcl-2 family (Mcl-1 and Bcl-xL) [46], anti-apoptotic proteins, and hexokinase 2 (HK2), which plays a central role in the cellular uptake and utilization of glucose [47]. The gene discussed is HK2; the disease is cancer.