Considering the results of molecular docking and the PLS-DA analysis, the alkaloids buphanidrine and powelline present in C. jagus belong to the group of alkaloids that could be responsible for the cytotoxic potential in gastric cancer AGS cells (Figure 3) due to the formation of hydrogen bridges and π interactions with the amino acid residues of HK-2 and Bcl-xL enzymes (Figure 5 and Figure 6). This evidence concerns the gene BCL2L1 and gastric cancer.