Representative class-I and II HLA alleles associated with sensitivity malaria are HLA-A*30:01, HLA-A*33:01, HLA-B*53:01, HLA-Cw*04:01, and HLA-DRB1*08:04, HLA-DRB1*13:02, and some alleles related to malaria resistance are HLA-B*53:01, HLA-DRB1*01:01, HLA-DQB1*05:01, HLA-DRB1*13:02, HLA-DRB1*13:01, HLA-DRB3*03:01, and HLA-DQA1*01:02, among others [32,33]. The gene discussed is HLA-B; the disease is malaria.