As changes in blood biochemical parameters, such as CRP, LDH and D-dimer, have been associated with the severity of COVID-19 [32], we analyzed the expression of IFNλs and IFNγ in SARS-CoV-2-infected patients stratified in two groups: those who had one or two parameters with increased levels (n = 15, group 1) and those who had enhanced levels of all three parameters (n = 15, group 2). This evidence concerns the gene IFNG and COVID-19.