IFNG and COVID-19: In light of these considerations, in order to provide additional insight concerning the expression of crosstalk between IFNλ and IFNγ production in COVID-19, we evaluated IFNλ and IFNγ gene expression in peripheral blood mononuclear cells (PBMCs) and bronchoalveolar lavage (BAL) cells collected from SARS-CoV-2-positive patients in terms of COVID-19 severity and outcome, the presence of bacterial superinfections and blood inflammatory marker levels.