In the case of a patient with diffuse large B-cell lymphoma (DLBCL) and iciHHV-6 integration in chromosome 17p the authors pointed out that structurally abnormal chromosomes are commonly found in DLBCL, and that the high expression of HHV-6 U94, a protein with DNA-binding, exonuclease, and helicase-ATP activities, may have been involved in tumorigenesis [77,78]. The gene discussed is SNORD94; the disease is diffuse large B-cell lymphoma.