AKT1 and lung cancer: Timosaponin AIII, as a glucosylated spirostane saponin of Anemarrhena asphodeloides (Asparagaceae) rhizomes, combated taxol-resistant lung cancer cells in vitro (2–8 μM) and in vivo (2.5 and 5 mg/Kg) via reducing PI3K/Akt/mTOR gene expressions [134].