Taking into account all these facts, it might be possible that a high dietary intake containing PUFAs, or the availability of PUFAs associated with colorectal cancer hypothesized by Song et al. [15], together with the upregulation on LCAT gene, could also be associated with an increment in ChoE synthesis that at the same time could be related with those higher levels of PUFAs observed previously in CRC patients [15]. Here, LCAT is linked to colorectal cancer.