VEGFA and hearing loss disorder: We previously studied common markers shared between HL and ARHL in an experimental model, demonstrating that noise-induced hearing loss can worsen/accelerate redox status imbalance including the increase of reactive oxygen species production; lipid peroxidation; dysregulation of endogenous antioxidant response, vascular dysfunction, such as increased expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in the cochlea, both of which are involved in the dysregulation of redox status and inflammatory pathway activation [3].