The baseline characteristics of safety included a few ARs such as palpitations (two patients in the SGLT-2i and GLP-1 RA groups, respectively), hypoglycemia (one patient in the SGLT-2i and GLP-1 RA groups, respectively), and those without gastrointestinal ARs or urinary tract infections, while the biologic parameters that were evaluated for the safety assessment were, respectively, creatinine, eGFR, UACR, urea, GOT, and GPT, and are also summarized in Table 3. The gene discussed is GCG; the disease is urinary tract infection.