GLP1R and diabetes mellitus: Our real-life study evaluated some of the most prescribed antidiabetic drugs, as they were, until recently, recommended by the standard-of-care of the American Diabetes Association (ADA), namely metformin, alongside two novel antidiabetic, non-insulinic drugs, SGLT-2is and GLP-1 RAs, respectively, which have become the first-line recommended antidiabetic drugs by the standard-of-care of the ADA [38].