TNFSF10 and neuroblastoma: In terms of the significance of ULK1 as a useful biomarker for assessing NB progression and metastasis, it can be argued since ULK1 has promoted resistance to anoikis, enhanced metastasis and countered TRAIL-mediated apoptosis [32]; therefore, it may be viewed as a potential biomarker to assess NB progression and metastasis.