Additional minor criteria for diagnosis include fever (40–80% of patients), increased erythrocyte sedimentation rate, high values for C-reactive protein, neutrophilic leukocytosis, responsiveness to systemic corticosteroids therapy, and the presence of a chronic inflammatory disorder, such as infection, pregnancy, malignancy, drug exposure, or myeloproliferative disorders [15]. This evidence concerns the gene CRP and myeloproliferative disorder.