Some specific settings can be modified by the patient such as the glucose target (default value 110 mg/dL, modifiable from 100 mg/dL to 130 mg/dL) and the hypoglycemia threshold for insulin suspension (default value 70 mg/dL, modifiable from 60 mg/dL to 85 mg/dL). The gene discussed is INS; the disease is Hypoglycemia.