The results predicted that the most prominent RA-associated genes were PIK3CA, PIK3CB, AKT1, AKT2, MAPK8, MAPK9, MAPK10, PRKCB, MAPK14, IGF1R, BRAF, PRKCZ, PRKCA, and NOS3 due to interaction of phytocannabinoids. Here, PRKCZ is linked to rheumatoid arthritis.