Namely, the appearance of new lesions (=any new focal uptake of PSMA-ligand higher than surrounding background, and each tumor SUVmax > mean SUVmean) and changes in PSMA-VOL (the total positive PSMA volume) were combined to develop RECIP 1.0, which included the classifications of response to therapy presented in Table 9. This evidence concerns the gene FOLH1 and neoplasm.