SUGT1 and colorectal cancer: One of its predicted targets is SGT1 homolog (SUGT1), a highly conserved protein generally found in the nucleus, involved in the kinetochore function and essential for the G1/S and G2M transition, which was shown to be increased in expression in the cytosolic fraction of the tumors in comparison to the tumor sample., The expression of this protein has been potentially linked with a poor prognosis in colorectal cancer [56].