ELN and osteoporosis: Similarly, miR-29, which is implicated in mammalian osteoblast differentiation targeting extracellular matrix molecules and modulating Wnt signaling and regulators of fibrogenesis in muscle targeting ECM proteins such as collagens, fibrillins, and elastin [95,96,97,98,99,100,101], was studied in only one study for both osteoporosis and sarcopenia.