For this reason, DPP-4 becomes a possible new interesting biomarker of liver damage in diabetic patients, due to the observation that DPP-4 is highly expressed in the liver, and its concentrations are positively correlated with liver function tests, as well as the correlation with the histopathologic degree of NASH and NAFLD [158]. This evidence concerns the gene DPP4 and metabolic dysfunction-associated steatohepatitis.