FGFR2 and esophageal adenocarcinoma: According to the Cancer Genome Atlas Research Network molecular classification data, 9% of chromosomal instability (CIN) and 8% of genomically stable (GS) gastric cancer subtypes harbored amplification of FGFR2 [2], while esophageal adenocarcinoma had amplification of FGFR1 or FGFR2 in 4% and 3% of the cases, respectively [12].