COL1A1 and fibrosis: Although Asp did not significantly alter the serological levels of Hyaluronic Acid (HA), Laminin (LN), COL III and COL IV in CCl4-induced fibrosis (Figure 1G), the co-treatment dramatically reduced the expression of histological indicators of fibrosis, such as α-SMA, COL1A1, COL1A2, and COL3A1, and hence, it ameliorates liver injury, as assessed by serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels (Figure 1F).