IL6 and COVID-19: A recent systematic review and meta-analysis has shown that IL-6 significantly increases the risk of COVID-19 severity (adjusted OR = 1.0284; 95% CI 1.0130–1.0441; p = 0.0003) and mortality (aOR = 1.0076; 95% CI 1.0004–1.0148; p = 0.04; adjusted hazard ratio (aHR) = 1.0036; 95% CI 1.0010–1.0061; p = 0.006) [19].