Moderate risk mutations in other genes affecting malignant transformation have also been highlighted: CHEK2 (effector kinase gene), PALB2 (BRCA2 protein stabilizer gene), RAD51C (RAD51 homolog C (S. cerevisiae)), NBN (previously known as NBS1), BRIP1 (protein gene that interacts with BRCA1), ATM and genes determining the occurrence of Lynch syndrome (MLH2, MSH1) [13,14,15]. The gene discussed is RAD51C; the disease is Lynch syndrome.