An analysis of 35 small nuclear polymorphisms in these genes from a Swedish population showed associations between KCNE1, KCNQ1, and KCNQ4 with NIHL [266], and a Polish study replicating the study found associations between polymorphisms in GJB1, GJB2, GJB4, KCNJ10, and KCNQ1 with NIHL [267]. The gene discussed is KCNQ1; the disease is noise induced hearing loss.