F8 and hemophilia: According to the Italian Association of Hemophilia Centers (AICE) recommendations on the dosage for the first FVIII infusion as prophylaxis of surgical bleeding in PWSHA on emicizumab, the ranges are the following: 50–100 IU/kg for major surgery, 30–40 IU/kg for minor surgery and 40–50 IU/kg for high-risk endoscopic procedures, respectively [8].