The use of adjuvant CT after CRS + HIPEC is considered beneficial, especially in the presence of any adverse prognostic factor (CCS ≥ 1, sarcomatoid or biphasic subtypes, lymph node metastases, high PCI or Ki-67 > 9%) [7]. The gene discussed is MKI67; the disease is metastatic malignant neoplasm in the lymph nodes.