Other lysosomal exoglycosidases have also been found to be possible alcohol markers, e.g., isoenzyme A, β-hexosaminidase (HEX A) as a marker of chronic alcohol consumption intensity, α-fucosidase (FUC) and α-mannosidase (MAN) as markers of alcohol dependence, and β-glucuronidase (GLU) as a marker of both these states simultaneously (intensity + relationship) [42]. This evidence concerns the gene HHEX and alcohol dependence.