CCL2 and diabetic kidney disease: In addition, cellular adhesion molecules including intracellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1) and E-selectin, chemokines including monocyte chemoattractant protein-1 (MCP-1), and cytokines including interleukin-6 (IL-6) are inflammatory mediators of renal injury in DKD [19].