Different studies suggested that RoT can inhibit tumor progression at several levels and in different cell models, inducing apoptosis, triggering cell cycle arrest, retarding cell migration and invasion in various types of human cancer [2] being an efficient compound against different tumor cells with multiple mechanisms of action [4], including inhibition of protein kinases with some specificity for Protein Kinase C [3]. The gene discussed is WEE1; the disease is neoplasm.