Four-week-old WT and Het male mice were randomly divided into four groups to test whether Mtfmt haploinsufficiency could alleviate metabolic disorders: WT and Het male mice were fed a high-fat diet (HFD, 60% fat; WT HFD and Het HFD, respectively) or a low-fat diet (LFD, 10% fat; WT LFD and Het LFD, respectively). Here, MTFMT is linked to Other metabolic disease.