Other anti-HER2 Nbs have also been labelled with various radioactive labels such as F-18 and Lu-177, with the former demonstrating high tumor-to-muscle/blood ratios allowing for the generation of high contrast PET images, and the latter demonstrating lesser radiation burden to non-target organs compared to a conventional mAb Lu-177 conjugate [115,116]. The gene discussed is ERBB2; the disease is neoplasm.