Complementary to this, human colon cancer cell lines may also express other efflux transporters, such as ABCG2 (breast cancer resistance protein, BCRP), ABCC3 (multidrug resistance-associated protein 3, MRP3) and ABCC2 (multidrug resistance-associated protein, MRP2) [221,222]. This evidence concerns the gene ABCC3 and colonic neoplasm.