Both of these play essential roles in the progression of PCa [22,23] As shown in Figure 3, the median TGF-β and IL-8 levels in patients with high frequencies of HER-2/neu(780–788)-specific CD8+ T lymphocytes were 35.73 ng/mL and 2.735 pg/mL (red circles), respectively. This evidence concerns the gene CD8A and posterior cortical atrophy.