γ-oscillations are 30-90 Hz bursts mainly generated in the cortical–subcortical brain regions, mainly by parvalbumin-positive γ-aminobutyric acid (GABA) interneurons, on the other side, have been demonstrated to be abnormal in post-mortem studies on schizophrenia patients, and animal modeling γ-oscillations have been shown to be deranged by N-methyl-D-aspartate receptor (NMDAR) blockade [58]. This evidence concerns the gene PVALB and schizophrenia.