For instance, 13 switch genes, GPNMB, TH, CD59, COL4A1, ZBTB16, TSPAN15, DMD, LEF1, GPR3, UBE2V1, DPP10, NECTIN2, LGALS3BP, CDKN1A, SERPINA1, and DMP1 were linked to AD, PD, FTD, PD dementia, Creutzfeldt Jakob disease, and LBD (Table 1). This evidence concerns the gene LGALS3BP and Alzheimer disease.