Several DEGs identified in F1 ovaries are related to human reproductive diseases, particularly DHCR24 (prepubertal growth retardation and adult infertility), DNAJA1 (defective androgen regulation in Sertoli cells leading to spermatid defects), FST (presence of male-specific coelomic vessels in ovary and loss of oocytes), TCF21 (infantile uterus, male infertile), Wt1 (somatic and germ cell lineages), ZP1 (defects in fertilization), and ZP2 (defects in oocytes in developmental competence) [97]. The gene discussed is TCF21; the disease is reproductive system disorder.