Advanced glycation end products (AGEs) is involved in the onset and exacerbation of Alzheimer’s disease while numerous studies favored that glycation help extracellular β-amyloid deposition as neuritic plaques and intracellular accumulation of hyperphosphorylated tau as neurofibrillary tangles [35,36]. This evidence concerns the gene MAPT and early-onset autosomal dominant Alzheimer disease.