As reported by Scioli et al. [14], who found a significant cytotoxic effect of adipose-derived MSCs loaded with PTX in human breast cancer cell lines, we demonstrated with enzymatic assays that MSC-CM PTX-induced cell apoptosis after 48 and 72 h was directly proportional to cleaved Caspase 3 protein levels in both human TNBC cell lines. This evidence concerns the gene CASP3 and breast carcinoma.