A study by Shi et al. demonstrated the association between ABCG2 expression in oral lichen ruber planus and an increased risk of malignant transformation in a sample of 110 patients, whereas Feng confirmed the potential of ABCG2 in predicting malignant transformation by analyzing ABCG2 expression in healthy oral mucosa, premalignant changes, and oral cavity cancer in 8 cell lines and 189 subjects [62,63]. This evidence concerns the gene ABCG2 and oral cavity cancer.