Common medications and medical conditions, which are related to secondary osteoporosis, include proton pump inhibitors (PPIs), hypogonadism and agents inducing hypogonadism, selective serotonin receptor inhibitors (SSRIs), chemotherapies, medroxyprogesterone acetate (MPA), antidepressants, anticonvulsants, inflammatory bowel disease, and thyroid hormone replacement or suppressive agents [9]. The gene discussed is TG; the disease is hypogonadism.