FZD2 and Friedreich ataxia: Ingenuity pathway analysis (IPA) of the colonocyte transcriptome revealed that the differentiation of FA with AD was best described by the genes in ‘Wnt/β-catenin Signaling’, specifically AXIN1, CCND1, FZD2, and WNT6, indicating that this mechanism might be regulated by Wnt signaling [112].