They showed that the expression of genes involved in the Imd pathway, such as Relish and AMPs (AttA, DptB), increased with age in the W1118 control flies and in the embryonic nervous system of AD transgenic flies Aβ42, tauWT, or tauR406W, but the level of AMPs in glia remarkably decreased compared to W1118. The gene discussed is ADSL; the disease is Alzheimer disease.