Azacitidine treatment of a primary UL culture decreases tumour cell viability (probably via hypomethylation/activation of tumour-suppressor genes), ECM production and the expression of genes encoding WISP1, c-MYC and MMP7 proteins, which are the targets of the WNT/β-catenin signalling pathway [285]. The gene discussed is MMP7; the disease is neoplasm.