ABCA7 and Alzheimer disease: Analysis of the ROC curve for ABCA7 mRNA expression as a biomarker for AD and AD-like disorders showed AUC values of 0.833 (66.7% sensitivity, 100% specificity, p = 0.006) (Figure 2J) and 0.828 (75% sensitivity, 100% specificity, p < 0.001) (Figure 2L).