By functionality, we grouped genes according to their function: regulator of energy metabolism (Gadd45a), apoptosis (Bcl2, Ier3), catabolic processes (Zfand2a), inflammation (Klkb1, Tnfrsf14), cell cycle control, and cancer (Csnk2a1, Cdc42, Rasa1, Prdx2, Tpr) (Table 1). This evidence concerns the gene IER3 and cancer.